Your Equine Needs Under One Roof

Your Equine Needs Under One Roof

Wednesday, October 17, 2007

CIRCULON PASTE

CIRCULON PASTE



EFFECTIVE AND SAFE VASODILATOR THERAPY.
For conditions of the lower limb that may benefit from improved blood flow.


CONTAINS ISOXSUPRINE HYDROCHLORIDE.
Expert a peripheral vasodilatory action on the blood vessels of the lower limb, distal to the carpus and the hock. Acts to reduce blood viscosity and improves erythrocyte deformation characteristics to re-establish flow in blocked or damaged vessels.


EASY TO ADMINISTER PASTE FORM.
Uniquely formulated paste ensures precise and accurate dosing. Paste formulation reduces the risk of contamination of other horses in stable due to powder sifting and drifting in air.


ANISEED FLAVOUR.
Pleasant taste improves ease and accuracy of dosing and minimises wastage.


EQUINE PHARMACEUTICAL
VASODILATOR
PROPERTIES
Vasodilator. Reduces blood viscosity. Aniseed flavoured paste.


ACTIVE CONSTITUENTS
Isoxsuprine hydrochloride 40mg/mL


PRESENTATION
Paste: 230mL bulk pot (with a 10mL oral dosing syringe).


INDICATIONS
As an aid in the treatment of conditions of the lower limb in horses, where vasodilation would be beneficial including:
Navicular Disease.
Pedal Osteitis.
Caudal heel syndrome.
Sesamoiditis.
Pedal bone fractures.
Damage to the coronary band.
Slow growing hooves / hoof repair.
Wound healing such as heel lacerations.


MODE OF ACTION
Isoxsuprine is adrenoceptor agonist causing vasodilation by relaxation of vascular smooth muscle. This dilating action is greater on the arteries supplying skeletal muscles than on those supplying the skin. It exerts a peripheral vasodilatory action on the blood vessels of a horse's lower limb, distal to the carpus and hock. It also produces positive inotropic effects, improves blood viscosity and erythrocyte deformation characteristics to re-establish blood flow in blocked or damaged arteries.


CONTRA-INDICATIONS
Do not use in pregnant mares, or within 14 days postpartum.
Do not administer following recent arterial haemorrhage.
Not to be given to horses intended for human consumption.

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